Dosimetric and Morbidity Outcomes of CS-131 Brachytherapy in Combination With External Beam Radiation Therapy in Subjects With Intermediate to High Risk Adenocarcinoma of the Prostate: An Observational Study

The purpose of this study is to scientifically evaluate the effects (good and bad) of a new type of radioactive treatment in patients with prostate cancer. The effects of placing a new type of small radioactive pellets (hereinafter called seeds) inside your prostate (brachytherapy), called Cesium –131 (Cs-131).

In particular, the treatment under study involves a seed implant with Cs-131 in addition to a course (a shortened cycle) of external beam radiation. It is widely believed that, for patients with “intermediate to high risk” prostate cancer, the combination of seed implant and external beam radiation offers a better chance of success than either treatment alone.

This research is being done to see what advantages, if any, Cs-131 may have over the other commonly used seeds, such as Iodine (I-125) and Palladium (Pd-103). This study will evaluate whether or not the usage of Cs-131 results in an improved delivery of radiation to the prostate and possibly a different side effect profile as compared to these other seeds.

For further information please contact: research@seattleprostate.com